For x86 apps, the
WOW64 layer of Windows allows x86 code to run on the Arm64 version of Windows, just as it allows x86 code to run on the x64 version of Windows. This means that x86 apps on Arm are protected with filesystem and registry redirection.
For x64 apps, there is no WOW64 layer and no separate registry or folder of Windows system binaries. Instead, system binaries are compiled as
Arm64X PE files that can be loaded into both x64 and Arm64 processes from the same location without the need for filesystem redirection.
This means that x64 applications can access the entire OS, both filesystem and registry, without the need for special code.