Solved Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item.


William654

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Hi

I start to get this message for all exe in my USB external HDD but if I moved the exe into my internal drives it run fine !!. I granted "everyone" full control access but did not solve it, any ideas ?
 

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Berton

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I have External USB drives and seldom have the problem but on occasion get the same type message when trying to open files in a program, usually office-type files. I can even run .exe programs for install from my NAS drive. It usually is because the files came from a 'foreign' computer.

I tried to update a diagnostic yesterday [that I've used for more than 15 years] from within the program but it called up Edge, one of the new things after Internet Explorer going away, Edge's security blocked it and had no option to do it anyway. I had to copy the URL and put it Firefox to get the download, obviously Edge is "helping" us in its own way.
 

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    Win11 Pro RTM
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    Manufacturer/Model
    Dell Vostro 3400
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    Intel Core i5
    Memory
    8GB
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    256GB SSD NVMe
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    Windows 11 Pro RTM x64
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    Manufacturer/Model
    Dell Vostro 5890
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    Intel Core i5
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johnlgalt

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Hi

I start to get this message for all exe in my USB external HDD but if I moved the exe into my internal drives it run fine !!. I granted "everyone" full control access but did not solve it, any ideas ?

It may not be the permission of the executable, but the permission of the folder that the executable is trying to run from,m that may be the issue. Also, are these portable programs that are made to run from any folder, or just programs that you've manually copied from their default installation locations to the USB drive?
 

My Computers

System One System Two

  • OS
    Windows 11 21H2 Current build
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    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * 32 GB - Corsair Vengeance 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D03 4K Gaming Monitor (Matte finish) | Eve Spectrum ES07DC9 4K Gaming Monitor (Glossy finish)
    Screen Resolution
    4K x2
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
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    Fractal Design Define 7 XL Dark ATX Full Tower Case
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    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
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    Defender
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    CHromeOS Flex v108 Dev
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    Dell Latitude E5470
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    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
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    Dell
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    16 GB
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    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
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    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
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William654

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It may not be the permission of the executable, but the permission of the folder that the executable is trying to run from,m that may be the issue. Also, are these portable programs that are made to run from any folder, or just programs that you've manually copied from their default installation locations to the USB drive?
I granted the permission of the parent folder and even the whole drive. They are setup files should run from anywhere.
 

My Computer

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  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    5900x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM750
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    Bloody rage
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    Water cooling gamdias 240
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johnlgalt

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But you granted permissions to yourself, whereas setup files need access via .. .SYSTEM level (or, probably TrustedInstaller, to be accurate) permissions. Being a USB drive, it might be problematic either from that perspective, or simply from the fact that security is preventing installations from running from USB devices in general to help prevent malware infections.
 

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  • OS
    Windows 11 21H2 Current build
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    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * 32 GB - Corsair Vengeance 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D03 4K Gaming Monitor (Matte finish) | Eve Spectrum ES07DC9 4K Gaming Monitor (Glossy finish)
    Screen Resolution
    4K x2
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3S
    Internet Speed
    AT&T LightSpeed Gigabit Duplex Ftth
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    CHromeOS Flex v108 Dev
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
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    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master 3S (shared w. Sys 1) | Dell TouchPad
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    Dell
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William654

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I tried again with normal exe app I got same error. System and my user admin also have full control access permission
 

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    CPU
    5900x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM750
    Case
    Bloody rage
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    Water cooling gamdias 240
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    razer ornata
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    razer da v2
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johnlgalt

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SO, I searched around and found a lot of different answers.

1) Check your Antivirus solution (if you're using a 3rd party solution) to see if it is blocking access to run executables form the USB drive.

2) Are you logged in with a Microsoft account or a 'local only' account?

3) Do you have the Multipoint Coonector feature enabled in Windows Features?

Open Start menu --> type Windows Features --> Select Turn Windows Features on and off --> scroll down to this:

246.png

If it is enabled, disable, then reboot, and see if you can run them from the USB now or not.
 
Last edited:

My Computers

System One System Two

  • OS
    Windows 11 21H2 Current build
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * 32 GB - Corsair Vengeance 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D03 4K Gaming Monitor (Matte finish) | Eve Spectrum ES07DC9 4K Gaming Monitor (Glossy finish)
    Screen Resolution
    4K x2
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3S
    Internet Speed
    AT&T LightSpeed Gigabit Duplex Ftth
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    CHromeOS Flex v108 Dev
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master 3S (shared w. Sys 1) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex Ftth

William654

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1- antivirus disabled and still same problem
2- Microsoft account
3- Multipoint Coonector feature enabled
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    5900x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM750
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
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    Malwarebytes

johnlgalt

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What I meant was to try disabling Multipoint Connector, as that was reported by one user as fixing your exact issue.
 

My Computers

System One System Two

  • OS
    Windows 11 21H2 Current build
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * 32 GB - Corsair Vengeance 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D03 4K Gaming Monitor (Matte finish) | Eve Spectrum ES07DC9 4K Gaming Monitor (Glossy finish)
    Screen Resolution
    4K x2
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3S
    Internet Speed
    AT&T LightSpeed Gigabit Duplex Ftth
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    CHromeOS Flex v108 Dev
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master 3S (shared w. Sys 1) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex Ftth

William654

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What I meant was to try disabling Multipoint Connector, as that was reported by one user as fixing your exact issue.
This solved the problem !! Many thanks.

Now I need your help here please
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    5900x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM750
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes

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