Solved Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item.


William654

Active member
Local time
4:07 AM
Posts
124
OS
Windows 11
Hi

I start to get this message for all exe in my USB external HDD but if I moved the exe into my internal drives it run fine !!. I granted "everyone" full control access but did not solve it, any ideas ?
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    3800x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM850
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes

Berton

Well-known member
Member
VIP
Local time
8:07 PM
Posts
565
Location
Wyoming
OS
Win11 Pro RTM x64
I have External USB drives and seldom have the problem but on occasion get the same type message when trying to open files in a program, usually office-type files. I can even run .exe programs for install from my NAS drive. It usually is because the files came from a 'foreign' computer.

I tried to update a diagnostic yesterday [that I've used for more than 15 years] from within the program but it called up Edge, one of the new things after Internet Explorer going away, Edge's security blocked it and had no option to do it anyway. I had to copy the URL and put it Firefox to get the download, obviously Edge is "helping" us in its own way.
 

My Computers

System One System Two

  • OS
    Win11 Pro RTM x64
    Computer type
    Laptop
    Manufacturer/Model
    Dell Vostro 3400
    CPU
    Intel Core i5
    Memory
    8GB
    Hard Drives
    256GB SSD NVMe
  • Operating System
    Windows 11 Pro
    Computer type
    PC/Desktop
    Manufacturer/Model
    Dell Vostro 5890
    CPU
    Intel Core i5
    Memory
    8GB [16GB on order]
    Monitor(s) Displays
    21"
    Hard Drives
    512GB SSD NVMe
    Browser
    Firefox, Edge
    Antivirus
    Windows Defender/Microsoft Security

johnlgalt

Antidisestablishmentarianistentarianist
Power User
VIP
Local time
10:07 PM
Posts
2,350
Location
3rd Rock
OS
Windows 11 21H2
Hi

I start to get this message for all exe in my USB external HDD but if I moved the exe into my internal drives it run fine !!. I granted "everyone" full control access but did not solve it, any ideas ?

It may not be the permission of the executable, but the permission of the folder that the executable is trying to run from,m that may be the issue. Also, are these portable programs that are made to run from any folder, or just programs that you've manually copied from their default installation locations to the USB drive?
 

My Computers

System One System Two

  • OS
    Windows 11 21H2
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * Corsair Vengeance 32 GB 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D02 280 Hz QHD | Eve Spectrum ES07D03 4K Gaming Monitor
    Screen Resolution
    1440p | 4k
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3 for Business
    Internet Speed
    Logitech MX Master 3 for Business
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    Windows 10 x64 Pro build 21H1
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master (shared) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex
    Browser
    Edge Chromium | Chrome | Firefox Nightly | Brave
    Antivirus
    Defender + MB4

William654

Active member
Thread Starter
Local time
4:07 AM
Posts
124
OS
Windows 11
It may not be the permission of the executable, but the permission of the folder that the executable is trying to run from,m that may be the issue. Also, are these portable programs that are made to run from any folder, or just programs that you've manually copied from their default installation locations to the USB drive?
I granted the permission of the parent folder and even the whole drive. They are setup files should run from anywhere.
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    3800x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM850
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes

johnlgalt

Antidisestablishmentarianistentarianist
Power User
VIP
Local time
10:07 PM
Posts
2,350
Location
3rd Rock
OS
Windows 11 21H2
But you granted permissions to yourself, whereas setup files need access via .. .SYSTEM level (or, probably TrustedInstaller, to be accurate) permissions. Being a USB drive, it might be problematic either from that perspective, or simply from the fact that security is preventing installations from running from USB devices in general to help prevent malware infections.
 

My Computers

System One System Two

  • OS
    Windows 11 21H2
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * Corsair Vengeance 32 GB 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D02 280 Hz QHD | Eve Spectrum ES07D03 4K Gaming Monitor
    Screen Resolution
    1440p | 4k
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3 for Business
    Internet Speed
    Logitech MX Master 3 for Business
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    Windows 10 x64 Pro build 21H1
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master (shared) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex
    Browser
    Edge Chromium | Chrome | Firefox Nightly | Brave
    Antivirus
    Defender + MB4

William654

Active member
Thread Starter
Local time
4:07 AM
Posts
124
OS
Windows 11
I tried again with normal exe app I got same error. System and my user admin also have full control access permission
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    3800x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM850
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes

johnlgalt

Antidisestablishmentarianistentarianist
Power User
VIP
Local time
10:07 PM
Posts
2,350
Location
3rd Rock
OS
Windows 11 21H2
SO, I searched around and found a lot of different answers.

1) Check your Antivirus solution (if you're using a 3rd party solution) to see if it is blocking access to run executables form the USB drive.

2) Are you logged in with a Microsoft account or a 'local only' account?

3) Do you have the Multipoint Coonector feature enabled in Windows Features?

Open Start menu --> type Windows Features --> Select Turn Windows Features on and off --> scroll down to this:

246.png

If it is enabled, disable, then reboot, and see if you can run them from the USB now or not.
 
Last edited:

My Computers

System One System Two

  • OS
    Windows 11 21H2
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * Corsair Vengeance 32 GB 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D02 280 Hz QHD | Eve Spectrum ES07D03 4K Gaming Monitor
    Screen Resolution
    1440p | 4k
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3 for Business
    Internet Speed
    Logitech MX Master 3 for Business
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    Windows 10 x64 Pro build 21H1
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master (shared) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex
    Browser
    Edge Chromium | Chrome | Firefox Nightly | Brave
    Antivirus
    Defender + MB4

William654

Active member
Thread Starter
Local time
4:07 AM
Posts
124
OS
Windows 11
1- antivirus disabled and still same problem
2- Microsoft account
3- Multipoint Coonector feature enabled
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    3800x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM850
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes

johnlgalt

Antidisestablishmentarianistentarianist
Power User
VIP
Local time
10:07 PM
Posts
2,350
Location
3rd Rock
OS
Windows 11 21H2
What I meant was to try disabling Multipoint Connector, as that was reported by one user as fixing your exact issue.
 

My Computers

System One System Two

  • OS
    Windows 11 21H2
    Computer type
    PC/Desktop
    Manufacturer/Model
    HomeBrew
    CPU
    AMD Ryzen 9 3950X
    Motherboard
    MSI MEG X570 GODLIKE
    Memory
    4 * Corsair Vengeance 32 GB 3600 MHz
    Graphics Card(s)
    EVGA GeForce RTX 3080 Ti XC3 ULTRA GAMING (12G-P5-3955-KR)
    Sound Card
    Realtek® ALC1220 Codec
    Monitor(s) Displays
    Eve Spectrum ES07D02 280 Hz QHD | Eve Spectrum ES07D03 4K Gaming Monitor
    Screen Resolution
    1440p | 4k
    Hard Drives
    3x Samsung 980 Pro NVMe PCIe 4 M.2 2 TB SSD (MZ-V8P2T0B/AM)
    PSU
    PC Power & Cooling’s Silencer Series 1050 Watt, 80 Plus Platinum
    Case
    Fractal Design Define 7 XL Dark ATX Full Tower Case
    Cooling
    ZXT KRAKEN Z73 73.11 CFM Liquid CPU Cooler (3x 120 mm push top) + Air 3x 140mm case fans (pull front) + 1x 120 mm (push back) and 1 x 120 mm (pull bottom)
    Keyboard
    SteelSeries Apex Pro Wired Gaming Keyboard
    Mouse
    Logitech MX Master 3 for Business
    Internet Speed
    Logitech MX Master 3 for Business
    Browser
    Nightly (default) + Firefox (stable),Chrome, Edge/ß/Dev/Canary
    Antivirus
    Defender
  • Operating System
    Windows 10 x64 Pro build 21H1
    Computer type
    Laptop
    Manufacturer/Model
    Dell Latitude E5470
    CPU
    Intel(R) Core(TM) i5-6300U CPU @ 2.40GHz, 2501 Mhz, 2 Core(s), 4 Logical Processor(s)
    Motherboard
    Dell
    Memory
    16 GB
    Graphics card(s)
    Intel(R) HD Graphics 520
    Sound Card
    Intel(R) HD Graphics 520 + RealTek Audio
    Monitor(s) Displays
    Dell laptop display 15"
    Screen Resolution
    1920 * 1080
    Hard Drives
    Toshiba 128GB M.2 22300 drive
    INTEL Cherryvill 520 Series SSDSC2CW180A 180 GB SATA III SSD
    PSU
    Dell
    Case
    Dell
    Cooling
    Dell
    Mouse
    Logitech MX Master (shared) | Dell TouchPad
    Keyboard
    Dell
    Internet Speed
    AT&T LightSpeed Gigabit Duplex
    Browser
    Edge Chromium | Chrome | Firefox Nightly | Brave
    Antivirus
    Defender + MB4

William654

Active member
Thread Starter
Local time
4:07 AM
Posts
124
OS
Windows 11
What I meant was to try disabling Multipoint Connector, as that was reported by one user as fixing your exact issue.
This solved the problem !! Many thanks.

Now I need your help here please
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    PC/Desktop
    CPU
    3800x
    Motherboard
    Asus tuf x570
    Memory
    32 GB G.Skill
    Graphics Card(s)
    RX 6800 XT
    Sound Card
    Creative Sound Blaster Z
    Monitor(s) Displays
    Acer and AOC QHD 120Hz
    Screen Resolution
    QHD
    Hard Drives
    2TB Intel 660p and 2TB Sabrent Rokect 4 plus nvme, 4TB HDD HGST
    PSU
    Corsair RM850
    Case
    Bloody rage
    Cooling
    Water cooling gamdias 240
    Keyboard
    razer ornata
    Mouse
    razer da v2
    Browser
    FF and Chrome
    Antivirus
    Malwarebytes
Top Bottom