ASUS Announces ExpertCenter PN54-S1 Mini PC

Brink · Oct 3, 2025

ASUS Pressroom:

Mini PC powered by the AMD Ryzen 200 Series processor delivers efficient multitasking and reliable 24/7 operation

Powered by the latest AMD Ryzen™ 200 Series processor that delivers responsive performance for boosted productivity and seamless content creation
Features six USB ports and supports up to four 4K displays; compact and versatile design makes it ideal for a wide range of business and commercial uses
Advanced security with biometric login and a discrete TPM to ensure sensitive data is protected

TAIPEI, Taiwan, October 3, 2025 — ASUS today announced ExpertCenter PN54-S1, a mini PC powered by the latest AMD Ryzen™ 200 Series processors. This mini PC handles everyday workloads easily, with robust performance and enterprise-grade security making it a reliable solution for businesses. With its 0.6-liter premium aluminum chassis, ExpertCenter PN54-S1 Mini PC offers exceptional capabilities in a small footprint, delivering a perfect combination of efficiency, flexibility, and 24/7 dependability.

Optimized for productivity and multitasking

The Ryzen 200 Series processor that powers ExpertCenter PN54-S1 Mini PC is built on the AMD Zen 4 architecture with up to eight high-performance CPU cores and support for up to 64GB of memory, ensuring low-latency multitasking for daily workloads. ExpertCenter PN54-S1 Mini PC provides up to 16 AI TOPS for responsive processing of AI tasks to support local AI operations such as voice recognition, image enhancement, and real-time translation.

ExpertCenter PN54-S1 Mini PC also features AMD Radeon™ 780M graphics. Built on the latest RDNA3 architecture, graphics performance is 54% better and energy-efficiency is 25% higher compared to the previous-generation PN53. This makes the mini PC ideal for AI-assisted graphics generation and business-related content creation.

Enterprise-grade features

ExpertCenter PN54-S1 Mini PC features a built-in fingerprint sensor for biometric logins and includes fTPM 2.0 or optional dTPM for hardware-level key management, complying with the latest Windows 11 security standards. For large-scale deployments, the optional ASUS Control Center software offers centralized device management to allow IT teams to monitor systems, manage software, and configure alerts with ease.

Voice recognition for seamless AI interaction

ExpertCenter PN54-S1 Mini PC includes a built-in speaker and microphone, providing users with clear and reliable communication without the need for external audio accessories. Functionalities such as Instant Meeting and Idea Recording empower teams to work and collaborate more efficiently. In addition, this mini PC includes a voice command feature for instant access to the AI assistant.

Built for business longevity

ExpertCenter PN54-S1 Mini PC has an aluminum chassis that features finely-etched details, giving it a premium, professional aesthetic. Toolless design means the cover can simply be unlatched to gain access to device internals for easy memory and storage upgrades.

Built for longevity, ExpertCenter PN54-S1 Mini PC meets multiple US MIL-STD-810H standards, undergoing rigorous extreme temperature, altitude and humidity tests. Whether used for digital signage, self-service kiosks, or enterprise IT applications, ExpertCenter PN54-S1 Mini PC ensures reliable round-the-clock performance and unwavering durability.

ExpertCenter PN54-S1 Mini PC is packed in FSC®-certified materials to align with enterprises’ ESG goals.

Specifications

	ASUS ExpertCenter PN54-S1 Mini PC	ASUS ExpertCenter PN54-S1 Kit
ASUS Logo	Yes	No
Color	Black	Black
OS support	Windows ®11 Home/ Pro 24H2 Windows® 11 IoT Enterprise	Windows®11 Home/ Pro 24H2 Windows® 11 IoT Enterprise
CPU	AMD Ryzen™ 7 260 processor, cTDP 45W AMD Ryzen™ 5 220 processor, cTDP 28W AMD Ryzen™ 3 210 processor, cTDP 28W	AMD Ryzen™ 7 260 processor, cTDP 45W AMD Ryzen™ 5 220 processor, cTDP 28W AMD Ryzen™ 3 210 processor, cTDP 28W
Chipset	Integrated	Integrated
Graphics	Integrated- AMD Radeon™ 780M/740M/740M Graphics	Integrated- AMD Radeon™ 780M/740M/740M Graphics
Memory	2 x SO-DIMM, DDR5-5600MHz memory (8 /16 / 32GB), up to 2 x 32GB	2 x SO-DIMM, DDR5-5600MHz memory (8 / 16 / 32GB), up to 2 x 32GB No memory installed during shipment
Storage	2 x M.2 2280 PCIe® Gen4x4, supports 256GB–2TB NVMe® SSD	2 x M.2 2280 PCIe® Gen4x4, supports 256GB–2TB NVMe® SSD No storage installed during shipment
Wireless Network	WiFi 7 MT7925, Bluetooth® 5.4 WiFi 6E MT7922, Bluetooth® 5.4	WiFi 7 MT7925, Bluetooth® 5.4 WiFi 6E MT7922, Bluetooth® 5.4
LAN	RTL8125BG, 2.5G LAN, 10/100/1000/2500Mbps	RTL8125BG, 2.5G LAN, 10/100/1000/2500Mbps
Audio	Realtek ALC 8233 1 x Internal Mono-Speaker with External Smart Amp 1 x Internal Digital Mics	Realtek ALC 8233 1 x Internal Mono-Speaker with External Smart Amp 1 x Internal Digital Mics
TPM	fTPM 2.0 or onboard TPM module	fTPM 2.0 or onboard TPM module
Card Reader	None	None
Front I/O Ports	1 Power button 1 x USB 3.2 Gen 2 Type-C® (10Gbps) 2 x USB 3.2 Gen 2 Type-A (10Gbps) 1 x Audio Jack (Line out/Mic in/Headphone out)	1 Power button 1 x USB 3.2 Gen 2 Type-C® (10Gbps) 2 x USB 3.2 Gen 2 Type-A (10Gbps) 1 x Audio Jack (Line out/Mic in/Headphone out)
Back I/O Ports	1 x USB4® Type-C® (Supports DisplayPort™ 2.1 and PD-in 100W, max. speed 40Gbps) 1 x USB 3.2 Gen 2 Type-A (10Gbps) 1 x USB 2.0 Gen 2 Type-A (5Gbps) 1 x HDMI® 2.1 (FRL)1 2 x DisplayPort™ 1.4 (8.1Gbps) 1 x 2.5G RJ45 LAN 1 x 2.5G RJ45 LAN (Optional) 1 x DC-in	1 x USB4® Type-C® (Supports DisplayPort™ 2.1 and PD-in 100W, max. speed 40Gbps) 1 x USB 3.2 Gen 2 Type-A (10Gbps) 1 x USB 2.0 Gen 2 Type-A (5Gbps) 1 x HDMI® 2.1 (FRL)1 2 x DisplayPort™ 1.4 (8.1Gbps) 1 x 2.5G RJ45 LAN 1 x 2.5G RJ45 LAN (Optional) 1 x DC-in
Side I/O Ports	1 x Kensington Lock	1 x Kensington Lock
Power Supply	20VDC /19VDC, 6.0A / 6.32A, 120W Power Adapter	20VDC /19VDC, 6.0A / 6.32A, 120W Power Adapter
Operating Temp	0°–40° C	0°–40° C
Storage Temp	-40°–60° C	-40°–60° C
Dimensions (W x D x H)	130 x 130 x 34mm	130 x 130 x 34mm
Weights	530g	530g
Accessories	AC Adapter + Power Cord VESA Bracket and Screws Safety/Caution/Regulatory Insert Warranty Card	AC Adapter + Power Cord VESA Bracket and Screws Safety/Caution/Regulatory Insert Warranty Card