Panda usb vaccine not working in 24H2


Good idea. I can't see Microsoft making an exception for a little program like that in 25H2 somehow though 🤣 But it's possible.
I meant that maybe they will have fixed whatever it is that is causing older programs not to run properly because there are indeed many.
 

My Computer

System One

  • OS
    Windows 11
    Computer type
    Laptop
    Manufacturer/Model
    Alienware A51M R2
    CPU
    Intel(R) Core(TM) i9-10900K CPU @ 3.70GHz
    Memory
    32,0 GB
    Graphics Card(s)
    Nvidia GeForce RTX2080 Super
    Sound Card
    Realtek
    Screen Resolution
    4K
    Hard Drives
    2TB (2x 1TB PCle M.2 SSD) RAID 0 [Boot] + 2TB (2x 1TB
    PCle M.2 SSD) Non-Raid [Storage]
You can always scan the USB manually. Most AVs will intercept malware on a USB only when it executes.
Yes and I do sometimes but this thing I had before was too fast for anything like that - it was instasnt as soon as the usb was in. That experience led to me using the Panda USB vaccine and I've used it ever since. If you don't tinker with other old laptops from different people, it probably isn't necessary! But there are still some nasties out there in the wild.

And this one got passed to a Windows 10 laptop only about 7 or 8 years ago.
 
Last edited:

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
I meant that maybe they will have fixed whatever it is that is causing older programs not to run properly because there are indeed many.
Thank you, yes I hope they do, if there are many issues like this - going back to 23H2 for now is an option. I just assumed it was a deliberate thing! Like removing wordpad and how windows 7 games used to get removed.
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
After some background research on Panda USB Vaccine, it's less mystifying than it appears.

1. Host protection is done by updating a reg (confirmed by RegistryChangesView):
Code:
Windows Registry Editor Version 5.00

[HKEY_LOCAL_MACHINE\Software\WOW6432Node\Microsoft\Windows NT\CurrentVersion\IniFileMapping\Autorun.inf]
@="@SYS:DoesNotExist"

2. USB autorun protection is done by creating a hidden file named AUTORUN_.INF, that has the Reserved attribute enabled. Panda is directly hacking the attribute byte on the FAT32 disk volume to set the flag, bypassing normal Windows which can't touch it.

If you have a (hex) disk editor, you can modify itself yourself, but I wouldn't do it unless you had a freshly formatted USB drive.
 

My Computer

System One

  • OS
    Windows 7
Thank you! I actually just asked Open AI as well and it said it could write a script that could do the same thing :-) Not sure I'd want to try that though. It was talking about making a file in Windows C: Root and adding a script to that.

What is hex disk editor? But yes I do have a freshly formatted usb stick :-)
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
Thank you! I actually just asked Open AI as well and it said it could write a script that could do the same thing :-) Not sure I'd want to try that though. It was talking about making a file in Windows C: Root and adding a script to that.

What is hex disk editor? But yes I do have a freshly formatted usb stick :-)
It edits an entire file (or disk volume) as one continuous stream of binary (or hexadecimal) byte data. Typically you need to know which exact bytes, and in which exact locations to edit.

But I found an even clearer article that duplicates USB Vaccine's work using CMD:
How To Immunize USB Flash Drive Against Autorun Viruses

Do this step on each fresh USB drive, and apply the reg file from above and you're basically there except for the "hiding on the systray" feature.
 

My Computer

System One

  • OS
    Windows 7
Last updated October 8, 2009? Time to move on! ;)
I'm not convinced 😂 And what harm is there in securing usb drives? Edit - control panel probably hasn't been updated since 2009 either 😂
 
Last edited:

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
It edits an entire file (or disk volume) as one continuous stream of binary (or hexadecimal) byte data. Typically you need to know which exact bytes, and in which exact locations to edit.

But I found an even clearer article that duplicates USB Vaccine's work using CMD:
How To Immunize USB Flash Drive Against Autorun Viruses

Do this step on each fresh USB drive, and apply the reg file from above and you're basically there except for the "hiding on the systray" feature.

This is what comes up on ninja pendisk when a usb drive is inserted - seems similar.

Ninja pendisk.webp
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
The posted article goes further than your snippet. It creates a subfolder using a reserved (no-no) named "CON". Windows Explorer and most API calls parse CON as the virtual device name for console (CON:).

Because any real malware isn't going to be fooled by changing the folder attributes to System / Hidden / Reserved. If you know that trick, the malware folks know it better than you.
 

My Computer

System One

  • OS
    Windows 7
So a query - some drives are already vaccinated with Panda - ie ones I don't want to format. Would using Ninja pendisk on them as well cause an issue? ie would it get done twice?
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
And what harm is there in securing usb drives?
Autorun was disabled in 10, so unless you are using XP, 7 or Vista , it does not really do anything.
Autorun is not quite the same thing as Autoplay. MS has disabled it by an update long time ago.
 

My Computer

System One

  • OS
    Home26H2Can
    Computer type
    PC/Desktop
    CPU
    AMD Ryzen 5 8600G (07/24)
    Motherboard
    ASROCK B650M-HDV/M.2 (07/24) BIOS 4.21 AGESA ComboAM5 1.3.0.1 (04/26)
    Memory
    2x32GB Kingston FURY DDR5 5600 MHz CL36 @5200 CL36 (07/24)
    Graphics Card(s)
    ASROCK Radeon RX 6600 Challenger D 8G @48FPS (08/24)
    Sound Card
    Creative Sound BlasterX AE-5 Plus (05/24)
    Monitor(s) Displays
    24" Philips 24M1N3200ZS/00 (05/24)
    Screen Resolution
    1920×1080@165Hz via DP1.4
    Hard Drives
    Kingston KC3000 NVMe 2TB (05/24)
    ADATA XPG GAMMIX S11 Pro 512GB (07/19)
    PSU
    Seasonic Core GM 550 Gold (04/24)
    Case
    Fractal Design Define 7 Mini with 3x Noctua NF-P14s/12@555rpm (04/24)
    Cooling
    Noctua NH-U12S with Noctua NF-P12 (04/24)
    Keyboard
    HP Pavilion Wired Keyboard 300 (07/24) + Rabalux 76017 Parker (01/24)
    Mouse
    Logitech M330 Silent Plus (01/26)
    Internet Speed
    500/100 Mbps via RouterOS (05/21) & TCP Optimizer
    Browser
    Edge, Brave for YouTube, LibreWolf for FB
    Antivirus
    NextDNS blocking 1/3 Traffic
    Other Info
    Phone: Motorola Moto G86 (02/26)
    Backup: Hasleo Backup Suite (PreOS)
    Headphones: Sennheiser RS170 (09/10)
    Chair: Huzaro Force 4.4 Grey Mesh (05/24)
    Notifier: Xiaomi Mi Band 9 Milanese (10/24)
    FlexCore USB-C 3.2 Gen 1 (M) to LAN (F) (08/25)
Autorun was disabled in 10, so unless you are using XP, 7 or Vista , it does not really do anything.
Autorun is not quite the same thing as Autoplay. MS has disabled it by an update long time ago.
Well I had a usb virus/worm jump to a Windows 10 computer! Hence I like to keep using the usb vaccine.
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
The posted article goes further than your snippet. It creates a subfolder using a reserved (no-no) named "CON". Windows Explorer and most API calls parse CON as the virtual device name for console (CON:).

Because any real malware isn't going to be fooled by changing the folder attributes to System / Hidden / Reserved. If you know that trick, the malware folks know it better than you.
So would it be possible to automate the example given on that page? Rather than do it manually each time?
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
Not sure about automating, but you call do this in a batch file as Administrator:

Immunize.bat D:
Immunize.bat D


Doesn't matter if you forgot the colon after the drive letter.
Code:
if "%~1"=="" exit /b 0

set "DRIVE=%1"
set "DRIVE=%DRIVE::=%"

if not exist %DRIVE%:\ (
    echo No drive %DRIVE% exists.
    exit /b 0
)

set "FOLDER=%DRIVE%:\autorun.inf"

del %FOLDER% /y
mkdir %FOLDER%
mkdir %FOLDER%\con\
attrib +h +r +s +a %FOLDER%
 

My Computer

System One

  • OS
    Windows 7
Just found that even if a drive is "vaccinated" by Panda - if I put it in my other machine (with Ninja pendisk), Ninja Pendisk vaccinates it again. Curious to know if it just overwrites what Panda did or adds something as well.

So the difference is, Panda includes the .con file (it seems - according to that article) and Ninja Pendisk doesn't.
 

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
I found this comment on the site below from 2012 (it refers to the fact the Bitdefender one (which is no longer available) can be bypassed) - but mainly explains why Panda USB vaccine wasn't updated. Because it worked.

"We have not updated Panda USB Vaccine in a long time because it works very good. Maybe DB has to update its vaccine because it is easily bypassed.

I don't have the time to do this again (I did it already some months ago), but I'm sure you can easily bypass BD yourself with a 2 or 3 liner cmd batch file to unhide and delete the BD "vaccine" (if it can be called that). Then try to do the same thing with Panda and you will see if won't work.

PS: we don't sell nor make any money out of Panda USB Vaccine. We thought it would help the community by giving it away for free, so the comment about being biased is really not correct. If you want the most secure solution, use Panda. If you want a lesser protection, use BD. Whichever you use I don't really care, I'm just giving you the facts."

 
Last edited:

My Computers

System One System Two

  • OS
    Windows 11 Home 25H2
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion 14-ce3606sa
    CPU
    Core i5-1035G1
    Memory
    32gb
    Hard Drives
    Samsung 870 evo sata ssd
    Cooling
    Could be better
    Internet Speed
    50 mbps Starlink
    Browser
    Firefox
    Other Info
    Originally came installed with a 500gb H10 Optane ssd
  • Operating System
    Windows 11 Home
    Computer type
    Laptop
    Manufacturer/Model
    HP Pavilion ce3606sa
    CPU
    Intel Core i5-1035G1
    Memory
    16gb
    Hard Drives
    Hynix Gold P31 2TB
    Internet Speed
    200mbps Starlink
    Browser
    Firefox
    Antivirus
    Defender
I hold the shift button when inserting a USB into a running Windows system.
If booting from one, that is a function of BIOS and not an issue.
I learn something new every day on this forum. Holding the shift key down while inserting a USB drive temporarily disables the AutoPlay feature, which is basically what the Panda USB Vaccine is doing. Cool! 😎
 

My Computers

System One System Two

  • OS
    Windows 11 Pro
    Computer type
    Laptop
    Manufacturer/Model
    Dell XPS 16 DA16260
    CPU
    Intel Series 3 Core Ultra X9 388H
    Memory
    64GB LPDDR5x 9600 MT/s
    Graphics Card(s)
    Intel Arc graphics B390 Panther Lake
    Monitor(s) Displays
    16" 3.2K Tandem OLED Infinity Edge
    Screen Resolution
    3200 x 2000 16:10 236 PPI
    Hard Drives
    1 Terabyte M.2 PCIe NVMe SSD
    Case
    Black Anodized Aluminum
    Cooling
    Vapor Chamber Cooling
    Mouse
    None
    Internet Speed
    942 Mbps Netgear Mesh + 2 Satellites
    Browser
    Microsoft Edge (Chromium)
    Antivirus
    Windows Security (Defender)
    Other Info
    NPU delivering 67 TOPS
    Microsoft 365 subscription
    Microsoft Office 365
    Microsoft OneDrive 1TB Cloud
    Microsoft Visual Studio
    Microsoft Visual Studio Code
    Microsoft Sysinternals Suite
    Microsoft BitLocker
    Microsoft Copilot
    Dell Support Assist
    Dell Command | Update
    Macrium Reflect X subscription
    1Password Password Manager
    Amazon Kindle for PC
    Lightroom/Photoshop subscription
    Interactive Brokers Trader Workstation
  • Operating System
    Windows 11 Pro
    Computer type
    Laptop
    Manufacturer/Model
    Microsoft Surface Laptop 7
    CPU
    Snapdragon® X Elite (12 Core) with Hexagon NPU delivering 45 TOPS
    Memory
    32GB LPDDR5x 8448 MT/s
    Graphics card(s)
    Integrated Adreno GPU
    Sound Card
    Omnisonic speakers with Dolby Atmos spatial sound
    Monitor(s) Displays
    13.8″ PixelSense Flow touchscreen 120 Hz 600 NIT
    Screen Resolution
    2304 × 1536 (201 PPI), 3:2 aspect ratio
    Hard Drives
    1 TB PCIe NVMe Gen 4 SSD
    Case
    Black Anodized Aluminum
    Cooling
    Vapor Chamber Cooling
    Mouse
    None
    Internet Speed
    942 Mbps Netgear Mesh + 2 Satellites
    Browser
    Microsoft Edge (Chromium)
    Antivirus
    Windows Security (Defender)
    Other Info
    Microsoft 365 subscription (Office)
    Microsoft Office 365
    Microsoft OneDrive 1TB Cloud
    Microsoft Visual Studio 2026
    Microsoft Visual Studio Code
    Interactive Brokers Trader Workstation
    Lightroom/Photoshop subscription
    1Password Password Manager
    Microsoft Sysinternals
    Amazon Kindle for PC
    Microsoft BitLocker
    Microsoft Copilot
On Windows 11 by default, AutoPlay is enabled but the AutoRun feature that is responsible for opening the (potentially malicious) Autorun.inf file automatically upon media insertion [if the medium in question has a root directory with an Autorun.inf file stored in it] is not configured. I.e., just like all the other AutoPlay options, by default this option is set to "Choose a default". (See the "Software" category at the bottom of the screenshot in this tutorial.) So, in essence, as long as you haven't changed this "Software" setting to "Install or run program from your media", whenever you insert a USB flash drive, Windows 11 neither will install nor will run the Autorun.inf file that could potentially leverage a spyware, adware, virus, worm, trojan, backdoor, ransomware, or other type of malware. However, also be aware that some USB devices are specially designed to look like USB flash drives, and some USB cables are specially designed to look like normal (data and/or charging) USB cables. To name only one example of this: USB Rubber Ducky.
 

My Computers

System One System Two

  • OS
    11 Home
    Computer type
    Laptop
    Manufacturer/Model
    Asus TUF Gaming F16 (2024)
    CPU
    i7 13650HX
    Memory
    16GB DDR5
    Graphics Card(s)
    GeForce RTX 4060 Mobile
    Sound Card
    Eastern Electric MiniMax DAC Supreme; Emotiva UMC-200; Astell & Kern AK240
    Monitor(s) Displays
    Sony Bravia XR-55X90J
    Screen Resolution
    3840×2160
    Hard Drives
    512GB SSD internal
    37TB external
    PSU
    Li-ion
    Cooling
    2× Arc Flow Fans, 4× exhaust vents, 5× heatpipes
    Keyboard
    Logitech K800
    Mouse
    Logitech G402
    Internet Speed
    30Mbit/s up, 500Mbit/s down
    Browser
    FF
    Antivirus
    What's an antivirus?
  • Operating System
    11 Home
    Computer type
    Laptop
    Manufacturer/Model
    Medion S15450
    CPU
    i5 1135G7
    Memory
    16GB DDR4
    Graphics card(s)
    Intel Iris Xe
    Sound Card
    Eastern Electric MiniMax DAC Supreme; Emotiva UMC-200; Astell & Kern AK240
    Monitor(s) Displays
    Sony Bravia XR-55X90J
    Screen Resolution
    3840×2160
    Hard Drives
    2TB SSD internal
    37TB external
    PSU
    Li-ion
    Keyboard
    Logitech K800
    Mouse
    Logitech G402
    Internet Speed
    30Mbit/s up, 500Mbit/s down
    Browser
    FF
Back
Top Bottom